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Articles

Page 3 of 384

  1. Fluid loading with crystalloids is the conventional treatment of major hemorrhage but might tend to create fluid overload. We studied hemodynamic profiles of fluid replacement therapies during major surgical h...

    Authors: François Jardot, Robert G. Hahn, Markus Huber and Patrick Y. Wuethrich
    Citation: Critical Care 2025 29:132
    Content type: Research Published on:

  3. Acute Respiratory Distress Syndrome (ARDS) is a leading cause of morbidity and mortality among critically ill patients, and mechanical ventilation (MV) plays a critical role in its management. One of the key p...

    Authors: Martín H. Benites, Fernando Suarez-Sipmann, Eduardo Kattan, Pablo Cruces and Jaime Retamal
    Citation: Critical Care 2025 29:130
    Content type: Review Published on:

  5. The definition of sepsis-associated acute kidney injury (SA-AKI) was updated in 2023. This study aims to describe the epidemiology of SA-AKI using updated consensus definition and to evaluate clinical outcomes.

    Authors: Tomonori Takeuchi, Alexander H. Flannery, Lucas J. Liu, Lama Ghazi, Augusto Cama-Olivares, Kiyohide Fushimi, Jin Chen, Sarah C. Huen, Ashita J. Tolwani and Javier A. Neyra
    Citation: Critical Care 2025 29:128
    Content type: Research Published on:

  7. Although haloperidol is commonly used to treat or prevent delirium in intensive care unit (ICU) patients, the evidence remains inconclusive. This study aimed to comprehensively evaluate the efficacy and safety...

    Authors: Shu-Li Cheng, Tien-Wei Hsu, Yu-Chen Kao, Chia-Ling Yu, Trevor Thompson, Andre F. Carvalho, Brendon Stubbs, Ping-Tao Tseng, Chih-Wei Hsu, Fu-Chi Yang, Yu-Kang Tu and Chih-Sung Liang
    Citation: Critical Care 2025 29:126
    Content type: Review Published on:

    The Matters Arising to this article has been published in Critical Care 2025 29:163

  8. In circulatory shock, tissue hypoperfusion leads to adverse outcomes. We hypothesized that peripheral tissue oxygen saturation (StO2), measured with near-infrared spectroscopy (NIRS), could provide a non-invasive...

    Authors: Elina Varis, Maria Heliste, Johanna Hästbacka, Suvi T. Vaara, Markus B. Skrifvars, Ville Pettilä, Mitja Lääperi, Anne Kuitunen, Annukka Vahtera and Erika Wilkman
    Citation: Critical Care 2025 29:125
    Content type: Research Published on:

  9. Rapid and reliable vascular access is crucial during cardiopulmonary resuscitation for out-of-hospital cardiac arrest (OHCA). While intraosseous (IO) and intravenous (IV) access are used, their comparative eff...

    Authors: Sanam Alilou, Ari Moskowitz and Sina Rashedi
    Citation: Critical Care 2025 29:124
    Content type: Research Published on:

  14. Post myocardial infarction ventricular septal defect (PMI-VSD) complicated by refractory cardiogenic shock is associated with an extremely high mortality rate. We sought to evaluate the factors associated with...

    Authors: Levi-Dan Azoulay, François Bagate, Clément Delmas, Sylvie Paulus, Nicolas Mongardon, Osama Abou-Arab, Pierre Squara, Michel Habis, Hélène Nougue, Tristan Morichau-Beauchant, Antoine Kimmoun, Aurélien Seemann, Costin Radu, Quentin de Roux, Henri Treille de Grandsaigne, Jean-Luc Fellahi…
    Citation: Critical Care 2025 29:119
    Content type: Research Published on:

  16. The manual entry of data into large patient databases requires significant resources and time. It is possible that a system that is enhanced with the technology of optical character recognition (OCR) can facil...

    Authors: Prompak Nitayavardhana, Keibun Liu, Kiyomitsu Fukaguchi, Mineto Fujisawa, Itaru Koike, Aina Tominaga, Yuta Iwamoto, Tadahiro Goto, Jacky Y. Suen, John F. Fraser and Pauline Yeung Ng
    Citation: Critical Care 2025 29:117
    Content type: Research Published on:

  18. Acute respiratory distress syndrome (ARDS) is a heterogeneous condition with varying response to prone positioning. We aimed to identify subphenotypes of ARDS patients undergoing prone positioning using machin...

    Authors: Maxime Fosset, Dario von Wedel, Simone Redaelli, Daniel Talmor, Nicolas Molinari, Julie Josse, Elias N. Baedorf-Kassis, Maximilian S. Schaefer and Boris Jung
    Citation: Critical Care 2025 29:116
    Content type: Research Published on:

  20. Cardiogenic shock (CS) is associated with high mortality and medical therapies have failed to improve survival. Treatment with lactate is associated with improved cardiac function which may benefit this condit...

    Authors: Oskar Kjærgaard Hørsdal, Mark Stoltenberg Ellegaard, Alexander Møller Larsen, Halvor Guldbrandsen, Niels Moeslund, Jacob Eifer Møller, Ole Kristian Lerche Helgestad, Hanne Berg Ravn, Henrik Wiggers, Roni Nielsen, Nigopan Gopalasingam and Kristoffer Berg-Hansen
    Citation: Critical Care 2025 29:113
    Content type: Research Published on:

  21. The impact of comorbidities on patients weaning from invasive ventilation is incompletely understood. We wished to understand the impact of the number and type of comorbidities on patients’ weaning from invasi...

    Authors: Omid Khazaei, Caoimhe M. Laffey, Rionach Sheerin, Bairbre A. McNicholas, Tài Pham, Leo Heunks, Giacomo Bellani, Laurent Brochard, Andrew J. Simpkin and John G. Laffey
    Citation: Critical Care 2025 29:114
    Content type: Research Published on:

  22. Nonagenarians and centenarians are a growing and vulnerable groups of patients admitted to ICU. There is limited information on their characteristics, outcomes, and complications.

    Authors: Je Min Suh, Nattaya Raykageeraroj, Boris Waldman, Nuanprae Kitisin, Cilla Haywood, Rinaldo Bellomo, Anoop N. Koshy, David Pilcher, Dong-Kyu Lee and Laurence Weinberg
    Citation: Critical Care 2025 29:112
    Content type: Review Published on:

  26. Delirium and postoperative cognitive dysfunction (POCD) are common complications post-cardiac surgery, yet no specific medical intervention is currently recommended for prevention. This study aimed to evaluate...

    Authors: Yun-Xiao Bai, Hui-Liang Wu, Wan-Li Xie, Xia Li, Jing-Jing Han, Jie Liu, Shi-Qiang Chen, Ping Yin, Nian-Guo Dong and Qing-Ping Wu
    Citation: Critical Care 2025 29:108
    Content type: Brief Report Published on:

  27. There are several approaches to select the optimal positive end-expiratory pressure (PEEP), resulting in different PEEP levels. The impact of different PEEP settings may extend beyond respiratory mechanics, af...

    Authors: Mayson L. A. Sousa, Luca S. Menga, Annia Schreiber, Mattia Docci, Fernando Vieira, Bhushan H. Katira, Mariangela Pellegrini, Sebastian Dubo, Ghislaine Douflé, Eduardo L. V. Costa, Martin Post, Marcelo B. P. Amato and Laurent Brochard
    Citation: Critical Care 2025 29:107
    Content type: Research Published on:

  28. Albumin kinetics in septic shock have been extensively studied, but clinical recommendations remain weak. An increased transcapillary escape rate (TER) of albumin has been demonstrated, though TER does not acc...

    Authors: Dag Seldén, Nicolas Tardif, Jan Wernerman, Olav Rooyackers and Åke Norberg
    Citation: Critical Care 2025 29:106
    Content type: Research Published on:

  29. The experience of patients under mechanical ventilation in the intensive care unit is described as complex and multifaceted, but an overarching and in-depth understanding of the experience is still missing.

    Authors: Fritz Sterr, Mareike Hechinger, Lydia Bauernfeind, Christian Rester, Rebecca Palm and Sabine Metzing
    Citation: Critical Care 2025 29:105
    Content type: Review Published on:

  31. This case report describes the successful treatment of a suicide attempt involving the ingestion of a supralethal dose of sodium azide (NaN3), presenting a prospective novel antidote and therapeutic approach. Tre...

    Authors: Jasper X. Geerdink, Greetje van der Wal, Lutea A. A. de Jong, Erik J. H. Olyslager, Thomas W. van den Goorbergh, Leo A. J. Kluijtmans and Peter E. Spronk
    Citation: Critical Care 2025 29:103
    Content type: Brief Report Published on:

  33. Early identification of patients with acute hypoxemic respiratory failure (AHRF) who are at risk of failing high-flow nasal cannula (HFNC) therapy could facilitate closer monitoring, and timely adjustment/esca...

    Authors: Hang Yu, Sina Saffaran, Roberto Tonelli, John G. Laffey, Antonio M. Esquinas, Lucas Martins de Lima, Letícia Kawano-Dourado, Israel S. Maia, Alexandre Biasi Cavalcanti, Enrico Clini and Declan G. Bates
    Citation: Critical Care 2025 29:101
    Content type: Research Published on:

  34. Head computed tomography (CT) is a routinely performed examination to assess the intracranial condition of patients with traumatic brain injury (TBI), and radiological findings can help to indicate the presenc...

    Authors: Yingchi Shan, Yajun Xue, Jun Zhu, Thijs Vande Vyvere, Dana Pisică, Andrew Maas, Shuo Zhang and Guoyi Gao
    Citation: Critical Care 2025 29:100
    Content type: Research Published on:

  36. Sepsis gene-expression sub-phenotypes with prognostic and theranostic potential have been discovered. These have been identified retrospectively and have not been translated to methods that could be deployed a...

    Authors: David B. Antcliffe, Estelle Peronnet, Frédéric Pène, Kristoffer Strålin, David Brealey, Sophie Blein, Richard Cleaver, Maria Cronhjort, Jean-Luc Diehl, Guillaume Voiriot, Aurore Fleurie, Claudia Lannsjö, Anne-Claire Lukaszewicz, Johan Mårtensson, Tài Pham, Nicolas De Prost…
    Citation: Critical Care 2025 29:98
    Content type: Research Published on:

  37. Diagnosing septic shock promptly is essential but challenging, especially due to its clinical similarity to non-septic shock. Extracellular vesicle-derived miRNAs may serve as biomarkers to distinguish septic ...

    Authors: Adrián García-Concejo, Belén Sánchez-Quirós, Esther Gómez-Sánchez, Laura Sánchez-de Prada, Álvaro Tamayo-Velasco, María Sherezade Tovar-Doncel, Mario Lorenzo, Estefanía Gómez-Pesquera, Rodrigo Poves-Álvarez, David Bernardo, Marta Martín-Fernández, Hugo Gonzalo-Benito, Paula Moreno-Portales, Rosa Prieto-Utrera, Miguel Bardají-Carrillo, Rocío López-Herrero…
    Citation: Critical Care 2025 29:96
    Content type: Research Published on:

  41. Fluid dynamics during and after a septic event is complex, but better knowledge could guide both fluid resuscitation and fluid removal. We aimed to compare fluid dynamics before and after sepsis in a clinicall...

    Authors: Son Ly Hong, Hugo Dumargne, Robert G. Hahn, Abdessalem Hammed, Romain Lac, Axel Guilpin, Charlotte Slek, Maxime Gerome, Bernard Allaouchiche, Vanessa Louzier and Auguste Dargent
    Citation: Critical Care 2025 29:92
    Content type: Research Published on:

  42. In critical illness, all elements of gut function are perturbed. Dysbiosis develops as the gut microbial community loses taxonomic diversity and new virulence factors appear. Intestinal permeability increases,...

    Authors: Danielle E. Soranno, Craig M. Coopersmith, Jessica F. Brinkworth, Faith N. F. Factora, Julia H. Muntean, Monty G. Mythen, Jacob Raphael, Andrew D. Shaw, Vidula Vachharajani and Jeannette S. Messer
    Citation: Critical Care 2025 29:91
    Content type: Consensus Article Published on:

  44. Authors: Alexandre Demoule, Amandine Baptiste, Arnaud W. Thille, Thomas Similowski, Stephanie Ragot, Gwénael Prat, Alain Mercat, Christophe Girault, Guillaume Carteaux, Thierry Boulain, Sébastien Perbet, Maxens Decavèle, Lisa Belin and Jean-Pierre Frat
    Citation: Critical Care 2025 29:89
    Content type: Correction Published on:

    The original article was published in Critical Care 2024 28:174

  45. Acute respiratory distress syndrome (ARDS) is a severe complication of critical illness, characterized by bilateral lung infiltrates and hypoxemia. Its clinical and pathophysiological heterogeneity poses chall...

    Authors: Lou’i Al-Husinat, Saif Azzam, Sarah Al Sharie, Mohammad Araydah, Denise Battaglini, Suhib Abushehab, Gustavo A. Cortes-Puentes, Marcus J. Schultz and Patricia R. M. Rocco
    Citation: Critical Care 2025 29:88
    Content type: Review Published on:

  47. In the Intensive Care Unit (ICU), clinicians frequently make complex, high-stakes judgments, where inaccuracies can profoundly affect patient outcomes. This perspective examines human judgment error in ICU set...

    Authors: I. P. Peringa, E. G. M. Cox, R. Wiersema, I. C. C. van der Horst, R. R. Meijer and J. Koeze
    Citation: Critical Care 2025 29:86
    Content type: Perspective Published on:

  49. Medication waste is a contributor to the healthcare environmental footprint and impacts ecosystems. Data on medication waste in the intensive care unit (ICU) are scarce, and therefore are essential to develop ...

    Authors: Erwan d’Aranda, Stéphanie Pons, Jonathan Chelly, Enora Atchade, Laure Bonnet, Claire Dahyot-Fizelier, Toufik Kamel, Fanny Giannoni, Olivier Collange, Emmanuel Besnier, Mathieu Schoeffler, Nicolas Mayeur, Pierre-Louis Quere, Ludivine Marecal, Cyril Pernod, Cyrille Geay…
    Citation: Critical Care 2025 29:84
    Content type: Research Published on:
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  • ISSN: 1364-8535 (electronic)

Critical Care

ISSN: 1364-8535