Your privacy, your choice

We use essential cookies to make sure the site can function. We also use optional cookies for advertising, personalisation of content, usage analysis, and social media.

By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some third parties are outside of the European Economic Area, with varying standards of data protection.

See our privacy policy for more information on the use of your personal data.

for further information and to change your choices.
Skip to main content

Articles

Page 4 of 384

  1. Mitigating environmental impacts is an urgent challenge supported by (scientific) intensive care societies worldwide. However, making green choices without compromising high-quality care for critically ill pat...

    Authors: Elisabeth Smale, Heather Baid, Marko Balan, Forbes McGain, Scott McAlistar, Jan J. de Waele, Jan Carel Diehl, Erik van Raaij, Michel van Genderen, Dick Tibboel and Nicole Hunfeld
    Citation: Critical Care 2025 29:80
    Content type: Perspective Published on:

  2. Infections are a leading cause of early mortality after liver transplantation (LT). Prior to transplantation, cirrhosis-associated immune dysfunction significantly increases the risk of infection. This study i...

    Authors: M. C. Delignette, A. Riff, T. Antonini, T. Soustre, M. Bodinier, E. Peronnet, F. Venet, M. Gossez, S. Pantel, J. Y. Mabrut, X. Muller, K. Mohkam, F. Villeret, D. Erard, J. Dumortier, F. Zoulim…
    Citation: Critical Care 2025 29:79
    Content type: Research Published on:

  3. Morphological analysis of intracranial pressure (ICP) pulse waveforms provides indirect information on cerebrospinal compliance, which might be reduced by space-occupying lesions but also by intracranial hyper...

    Authors: Magdalena Kasprowicz, Cyprian Mataczyński, Agnieszka Uryga, Adam I. Pelah, Eric Schmidt, Marek Czosnyka and Agnieszka Kazimierska
    Citation: Critical Care 2025 29:78
    Content type: Research Published on:

  5. Serum cardiac troponin (cTn) elevation is a well-established phenomenon in sepsis. However, the clinical significance of this phenomenon with high-sensitivity (hs) assays and the current sepsis definition need...

    Authors: Abraham I. J. Gajardo, Santiago Ferrière-Steinert, Joaquín Valenzuela Jiménez, Sebastián Heskia Araya, Thomas Kouyoumdjian Carvajal, José Ramos-Rojas and Juan Nicolás Medel
    Citation: Critical Care 2025 29:76
    Content type: Research Published on:

    The Matters Arising to this article has been published in Critical Care 2025 29:118

  6. Authors: Annalisa Boscolo, Andrea Bruni, Marco Giani, Eugenio Garofalo, Nicolò Sella, Tommaso Pettenuzzo, Michela Bombino, Matteo Palcani, Emanuele Rezoagli, Matteo Pozzi, Elena Falcioni, Elisa Pistollato, Eugenio Biamonte, Francesco Murgolo, Graziella D’Arrigo, Mercedes Gori…
    Citation: Critical Care 2025 29:75
    Content type: Correction Published on:

    The original article was published in Critical Care 2024 28:279

  8. The p-value has changed from a versatile tool for scientific reasoning to a strict judge of medical information, with the usual 0.05 cutoff frequently deciding a study’s significance and subsequent clinical use. ...

    Authors: Sharad Patel and Adam Green
    Citation: Critical Care 2025 29:73
    Content type: Perspective Published on:

    The Matters Arising to this article has been published in Critical Care 2025 29:135

  9. Large language models (LLMs) show increasing potential for their use in healthcare for administrative support and clinical decision making. However, reports on their performance in critical care medicine is la...

    Authors: Jessica D. Workum, Bas W. S. Volkers, Davy van de Sande, Sumesh Arora, Marco Goeijenbier, Diederik Gommers and Michel E. van Genderen
    Citation: Critical Care 2025 29:72
    Content type: Research Published on:

  10. Despite widespread vaccination programs, pertussis continues circulating within populations and remains a life-threatening infection in infants. While several mortality risk factors have been described, a comp...

    Authors: Vladimir L. Cousin, Caroline Caula, Jason Vignot, Raphael Joye, Matthieu Blanc, Clémence Marais and Pierre Tissières
    Citation: Critical Care 2025 29:71
    Content type: Research Published on:

  13. Airway mucus is a highly specialised secretory fluid which functions as a physical and immunological barrier to pathogens whilst lubricating the airways and humifying atmospheric air. Dysfunction is common dur...

    Authors: Thomas Roe, Thomas Talbot, Isis Terrington, Jayant Johal, Ivan Kemp, Kordo Saeed, Elizabeth Webb, Rebecca Cusack, Michael P. W. Grocott and Ahilanandan Dushianthan
    Citation: Critical Care 2025 29:68
    Content type: Review Published on:

  14. The optimal hemoglobin (Hb) threshold to trigger red blood cell transfusions (RBCT) in subarachnoid hemorrhage (SAH) patients is unclear. This study evaluated the impact of liberal versus restrictive transfusi...

    Authors: Chahnez Taleb, Elisa Gouvea Bogossian, Carla Bittencour Rynkowski, Kirsten Møller, Piet Lormans, Manuel Quintana Diaz, Anselmo Caricato, Luigi Zattera, Pedro Kurtz, Geert Meyfroidt, Herve Quintard, Maria Celeste Dias, Angelo Giacomucci, Charlotte Castelain, Russell Chabanne, Pilar Marcos-Neira…
    Citation: Critical Care 2025 29:67
    Content type: Research Published on:

  15. Postoperative sepsis is a severe complication associated with increased mortality and potential long-term cognitive decline, including dementia. However, the relationship between postoperative sepsis and demen...

    Authors: Mingyang Sun, Fangfang Li, Yangyang Wang, Mengrong Miao, Zhongyuan Lu, Wan-Ming Chen, Szu-Yuan Wu and Jiaqiang Zhang
    Citation: Critical Care 2025 29:66
    Content type: Research Published on:

  16. Although potent P2Y12 inhibitors, such as ticagrelor and prasugrel, are standard treatment in patients with acute myocardial infarction (AMI), evidence for their efficacy and safety compared with clopidogrel is l...

    Authors: Jinhwan Jo, Seung Hun Lee, Hyun Sung Joh, Hyun Kuk Kim, Ju Han Kim, Young Joon Hong, Young Keun Ahn, Myung Ho Jeong, Seung Ho Hur, Doo-Il Kim, Kiyuk Chang, Hun Sik Park, Jang-Whan Bae, Jin-Ok Jeong, Yong Hwan Park, Kyeong Ho Yun…
    Citation: Critical Care 2025 29:65
    Content type: Research Published on:

  17. Assessing and quantifying recruitability are important for characterizing ARDS severity and for reducing or preventing the atelectrauma caused by the cyclic opening and closing of pulmonary units. Over the yea...

    Authors: Stefano Giovanazzi, Domenico Nocera, Giulia Catozzi, Francesca Collino, Massimo Cressoni, Lorenzo Ball, Onnen Moerer, Michael Quintel, Luigi Camporota and Luciano Gattinoni
    Citation: Critical Care 2025 29:64
    Content type: Review Published on:

  18. Time to positivity (TTP) and differential TTP (DTP) emerge as diagnostic and prognostic tools for bloodstream infections (BSI) though specific cut-off values need to be determined for each pathogen. Pseudomonas a...

    Authors: Daniel N. Marco, Maria Brey, Sergi Anguera, Cristina Pitart, Ignacio Grafia, Marta Bodro, Jose Antonio Martínez, Ana del Río, Carolina Garcia-Vidal, Abiu Sempere, Celia Cardozo, Pedro Puerta-Alcalde, Mariana Chumbita, Marta Hernández-Meneses, Guillermo Cuervo, Patricia Monzo-Gallo…
    Citation: Critical Care 2025 29:63
    Content type: Research Published on:

    The Matters Arising to this article has been published in Critical Care 2025 29:143

    The Matters Arising to this article has been published in Critical Care 2025 29:94

  19. Relatives of intensive care unit (ICU) patients often endure symptoms of post-traumatic stress, anxiety, and depression during and after treatment of a family member’s hospitalization. The aim of this study wa...

    Authors: Denzel L. Q. Drop, Johan H. Vlake, Evert-Jan Wils, Jasper Van Bommel, Christian Jung, Denise E. Hilling, O. Joseph Bienvenu, Tim I. M. Korevaar, Anna F. C. Schut, Margo M. C. van Mol, Diederik Gommers and Michel E. van Genderen
    Citation: Critical Care 2025 29:62
    Content type: Research Published on:

  21. Passive leg raising (PLR) is a well-recognized method for assessing volume responsiveness in the intensive care unit (ICU); however, it has some limitations. The physiology of the cardiac preload induced by th...

    Authors: Zhiyong Wang, Jie Zhang, Jing Zhao, Yaxuan Wu, Shiya Zhang, Chengfen Yin, Xinjing Gao and Lei Xu
    Citation: Critical Care 2025 29:60
    Content type: Research Published on:

  22. Neutrophils release neutrophil extracellular traps (NETs) as part of a healthy host immune response. NETs physically trap and kill pathogens as well as activating and facilitating crosstalk between immune cell...

    Authors: Andrew Retter, Mervyn Singer and Djillali Annane
    Citation: Critical Care 2025 29:59
    Content type: Review Published on:

  23. The application of sepsis subtypes to enhance personalized medicine in critically ill patients is hindered by the lack of validation across diverse cohorts and the absence of a simple classification model. We ...

    Authors: Rombout B. E. van Amstel, Emma Rademaker, Jason N. Kennedy, Lieuwe D. J. Bos, Hessel Peters-Sengers, Joe M. Butler, Niklas Bruse, Dave A. Dongelmans, Matthijs Kox, Alexander P. J. Vlaar, Tom van der Poll, Olaf L. Cremer, Christopher W. Seymour and Lonneke A. van Vught
    Citation: Critical Care 2025 29:58
    Content type: Research Published on:

  24. Capillary refill time (CRT) and skin blood flow (SBF) have been reported to be strong predictors of mortality in critically ill patients. However, the relationship between both parameters remains unclear.

    Authors: Alexandra Morin, Louai Missri, Tomas Urbina, Vincent Bonny, Maxime Gasperment, Juliette Bernier, Jean-Luc Baudel, Eduardo Kattan, Eric Maury, Jérémie Joffre and Hafid Ait-Oufella
    Citation: Critical Care 2025 29:57
    Content type: Research Published on:

  26. Pathogen identification is essential in sepsis and septic shock. Metagenomic next-generation sequencing (mNGS) is a novel pathogen detection method with several advantages over traditional tests. However, the ...

    Authors: Chengxi Liu, Xiao Song, Jihai Liu, Liang Zong, Tao Xu, Xu Han, Fan Li, Bo Li, Huadong Zhu and Di Shi
    Citation: Critical Care 2025 29:55
    Content type: Review Published on:

  27. To use natural language processing (NLP) to study the incidence, characteristics, trajectory, associations, and outcomes of hallucinations and disturbed behaviour in intensive care unit (ICU) patients.

    Authors: Thomas Niccol, Marcus Young, Natasha E. Holmes, Kartik Kishore, Sobia Amjad, Michele Gaca, Rinaldo Bellomo and Ary Serpa Neto
    Citation: Critical Care 2025 29:54
    Content type: Research Published on:

  29. Ulinastatin (UTI), recognized for its anti-inflammatory properties, holds promise for patients undergoing cardiac surgery. This study aimed to investigate the relationship between intraoperative UTI administra...

    Authors: Xiao Ran, Tingting Xu, Jieqiong Liu, Shaobing Yang, Fang Luo, Rongxue Wu, Juan Tan, Hang Ruan and Qin Zhang
    Citation: Critical Care 2025 29:52
    Content type: Research Published on:

  32. In severely injured trauma patients, hypofibrinoginaemia is associated with increased mortality. There is no evidence-based consensus for what constitutes optimal fibrinogen therapy, treatment dose or timing o...

    Authors: Tom Burt, Ashley Guilliam, Elaine Cole and Ross Davenport
    Citation: Critical Care 2025 29:49
    Content type: Research Published on:

  33. As compared to withholding parenteral nutrition (PN) until one week after intensive care unit (ICU) admission, Early PN prolonged ICU dependency in the EPaNIC randomized controlled trial (RCT). The Refeeding R...

    Authors: C. Lauwers, L. Langouche, P. J. Wouters, A. Wilmer, G. Van den Berghe, M. P. Casaer and J. Gunst
    Citation: Critical Care 2025 29:48
    Content type: Research Published on:

  34. Advanced respiratory monitoring through the measurement of esophageal pressure (Pes) as a surrogate of pleural pressure helps guiding mechanical ventilation in ICU patients. Pes measurement with an esophageal ...

    Authors: Julien P. van Oosten, Nico Goedendorp, Amne Mousa, Rutger C. Flink, Rik Schaart, Merel Flinsenberg, Peter Somhorst, Diederik A. M. P. J. Gommers, Leo Heunks and Annemijn H. Jonkman
    Citation: Critical Care 2025 29:47
    Content type: Research Published on:

  39. Conflicting data exist regarding sex-specific outcomes after cardiac arrest. This study investigates sex disparities in the provision of critical care and outcomes of in-hospital (IHCA) and out-of-hospital car...

    Authors: Simon A. Amacher, Tobias Zimmermann, Pimrapat Gebert, Pascale Grzonka, Sebastian Berger, Martin Lohri, Valentina Tröster, Ketina Arslani, Hamid Merdji, Catherine Gebhard, Sabina Hunziker, Raoul Sutter, Martin Siegemund and Caroline E. Gebhard
    Citation: Critical Care 2025 29:42
    Content type: Research Published on:

  40. In-hospital cardiac arrest (IHCA) poses a considerable threat to hospitalized patients, leading to high mortality rates and severe neurological deficits among survivors. Despite the advancements in resuscitati...

    Authors: Feng-Cheng Chang, Ming-Jer Hsieh, Jih-Kai Yeh, Victor Chien-Chia Wu, Yu-Ting Cheng, An-Hsun Chou, Chia-Pin Lin, Chip‐Jin Ng, Shao-Wei Chen and Chun-Yu Chen
    Citation: Critical Care 2025 29:41
    Content type: Research Published on:

  42. Critical care nurses are vulnerable to depression, which not only lead to poor well-being and increased turnover intention, but also affect their working performances and organizational productivity as well. W...

    Authors: Xuting Li, Yusheng Tian, Jiaxin Yang, Meng Ning, Zengyu Chen, Qiang Yu, Yiting Liu, Chongmei Huang and Yamin Li
    Citation: Critical Care 2025 29:39
    Content type: Research Published on:

    The Matters Arising to this article has been published in Critical Care 2025 29:61

  43. Rapid, adequate treatment is crucial to reduce mortality in sepsis. Risk stratification scores used at emergency departments (ED) are limited in detecting all septic patients with increased mortality risk. We ...

    Authors: Maria Andersson, Karin Fröderberg Schooner, Viktor Karlsson Werther, Thomas Karlsson, Lina De Geer, Daniel B. Wilhelms, Martin Holmbom, Mats Fredrikson, Åse Östholm, Sören Berg and Håkan Hanberger
    Citation: Critical Care 2025 29:38
    Content type: Research Published on:

  44. Microcirculatory alterations are predictive of poor outcomes in patients with shock and after cardiac arrest in animal models. However, microcirculatory alterations during human cardiac arrest have not yet bee...

    Authors: Matthias Mueller, Michael Holzer, Heidrun Losert, Daniel Grassmann, Florian Ettl, Mathias Gatterbauer, Ingrid Magnet, Alexander Nuernberger, Calvin Lukas Kienbacher, Georg Gelbenegger, Michael Girsa, Harald Herkner and Mario Krammel
    Citation: Critical Care 2025 29:37
    Content type: Research Published on:

  45. Aneurysmatic subarachnoid hemorrhage (aSAH) is a critical condition associated with significant mortality rates and complex rehabilitation challenges. Early prediction of functional outcomes is essential for o...

    Authors: Masamichi Moriya, Kenji Karako, Shogo Miyazaki, Shin Minakata, Shuhei Satoh, Yoko Abe, Shota Suzuki, Shohei Miyazato and Hikaru Takara
    Citation: Critical Care 2025 29:36
    Content type: Research Published on:

  47. Intermediate care units (IMCUs) provide care for patients who need more intensive treatment than general wards but less than intensive care units (ICUs). Although the concept of an IMCU requires co-location wi...

    Authors: Hiroyuki Ohbe, Daisuke Kudo, Yuya Kimura, Hiroki Matsui, Hideo Yasunaga and Shigeki Kushimoto
    Citation: Critical Care 2025 29:34
    Content type: Research Published on:

  48. Phospholipid transfer protein (PLTP), a glycoprotein widely expressed in the body, is primarily involved in plasma lipoprotein metabolism. Previous research has demonstrated that PLTP can exert anti-inflammato...

    Authors: Wei Jiang, Lin Song, Weilei Gong, Xianghui Li, Keran Shi, Luanluan Li, Chuanqing Zhang, Jing Wang, Xiaolan Xu, Haixia Wang, Xiaoyan Wu, Jun Shao, Yang Yu, Jiangquan Yu and Ruiqiang Zheng
    Citation: Critical Care 2025 29:33
    Content type: Research Published on:

    The Matters Arising to this article has been published in Critical Care 2025 29:127

    The Matters Arising to this article has been published in Critical Care 2025 29:83

  49. Authors: Youn‑Jung Kim, Yong Hwan Kim, Chun Song Youn, In Soo Cho, Su Jin Kim, Jung Hee Wee, Yoo Seok Park, Joo Suk Oh, Byung Kook Lee and Won Young Kim
    Citation: Critical Care 2025 29:31
    Content type: Correction Published on:

    The original article was published in Critical Care 2023 27:313

  50. Low-volume hypertonic solutions, such as half-molar lactate (LAC), may be a potential treatment used for fluid resuscitation. This study aimed to evaluate the underlying cardiovascular effects and mechanisms o...

    Authors: Kristoffer Berg-Hansen, Nigopan Gopalasingam, Mette Glavind Bülow Pedersen, Jakob Tobias Nyvad, Nikolaj Rittig, Esben Søndergaard, Henrik Wiggers, Niels Møller and Roni Nielsen
    Citation: Critical Care 2025 29:30
    Content type: Research Published on:

    The Matters Arising to this article has been published in Critical Care 2025 29:217

    The Matters Arising to this article has been published in Critical Care 2025 29:166

CC logo
Submit manuscript

Follow

  • ISSN: 1364-8535 (electronic)

Critical Care

ISSN: 1364-8535