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Table 1 Included studies’ characteristics

From: Individualized mean arterial pressure targets in critically ill patients guided by non-invasive cerebral-autoregulation: a scoping review

Study characteristics

No. of studies, n (%)

Total number of included studies

49 (100)

Study design

Observational

45 (92)

Interventional physiology

2 (4)

Randomized controlled trial

2 (4)

Publication year

2000–2009

3 (6)

2010–2014

10 (20)

2015–2019

20 (41)

2020–2023

16 (32)

Setting*

Operating room (OR)

29 (59)

Intensive Care Unit (ICU)

17 (35)

Neurocritical Care Unit (NCCU)

5 (10)

Unknown/Department of Infectious Disease

1 (2)

Patients Characteristics

 

Cardiac Surgery

26 (53)

Non-Cardiac Major Surgery

4 (8)

Cardiac Arrest

7 (14)

Brain Injury

5 (10)

Respiratory Failure & Shock

3 (6)

Sepsis

2 (4)

Acute Bacterial Meningitis

1 (2)

Mixed

1 (2)

Study Objectives as Relates to Personalized MAP targets**

 Characterize personalized targets or the feasibility of identifying personalized targets

12 (24)

 Test and compare methods to improve personalized targets parameters calculations

15 (31)

 Compare personalized targets parameters by setting or intervention (ICU vs operative room, HCA, sevoflurane anesthesia, temporality of surgery/disease stage)

8 (16)

 Test the association between personalized targets parameters and clinical characteristics or outcomes

24 (49)

 Test the underlying physiology of personalized target parameters (e.g., vascular biomarkers, left–right lobe differences)

3 (6)

Newcastle–Ottawa Scale/JBI/Cochrane Risk of bias Score***

 Low

22

 Mid

25

 High

2

  1. *This refers to the setting where monitoring necessary for personalized target identification was performed. In some studies, multiple settings were possible (e.g., patient was monitored both in the OR and ICU and one target were calculated for each setting)
  2. **These may not be the primary objectives of the studies, and some studies have multiple objectives
  3. ***For Newcastle–Ottawa Scale, scores ≥ 7–9, 4–6, < 4 are considered low, intermediate, and high risk, respectively [26]. For JBI checklist, "Yes" answers for ≥ 8, 5–8, < 5 items are considered low, intermediate, and high risk, respectively