Study characteristics | No. of studies, n (%) |
---|---|
Total number of included studies | 49 (100) |
Study design | |
Observational | 45 (92) |
Interventional physiology | 2 (4) |
Randomized controlled trial | 2 (4) |
Publication year | |
2000–2009 | 3 (6) |
2010–2014 | 10 (20) |
2015–2019 | 20 (41) |
2020–2023 | 16 (32) |
Setting* | |
Operating room (OR) | 29 (59) |
Intensive Care Unit (ICU) | 17 (35) |
Neurocritical Care Unit (NCCU) | 5 (10) |
Unknown/Department of Infectious Disease | 1 (2) |
Patients Characteristics | |
Cardiac Surgery | 26 (53) |
Non-Cardiac Major Surgery | 4 (8) |
Cardiac Arrest | 7 (14) |
Brain Injury | 5 (10) |
Respiratory Failure & Shock | 3 (6) |
Sepsis | 2 (4) |
Acute Bacterial Meningitis | 1 (2) |
Mixed | 1 (2) |
Study Objectives as Relates to Personalized MAP targets** | |
Characterize personalized targets or the feasibility of identifying personalized targets | 12 (24) |
Test and compare methods to improve personalized targets parameters calculations | 15 (31) |
Compare personalized targets parameters by setting or intervention (ICU vs operative room, HCA, sevoflurane anesthesia, temporality of surgery/disease stage) | 8 (16) |
Test the association between personalized targets parameters and clinical characteristics or outcomes | 24 (49) |
Test the underlying physiology of personalized target parameters (e.g., vascular biomarkers, left–right lobe differences) | 3 (6) |
Newcastle–Ottawa Scale/JBI/Cochrane Risk of bias Score*** | |
Low | 22 |
Mid | 25 |
High | 2 |