From: 44th International Symposium on Intensive Care & Emergency Medicine
Variables | Ventilation strategy | Odds ratio (95% CI) or absolute difference (95% CI) | p value Unadjusted | |
---|---|---|---|---|
Sigh (n = 96) | Conventional (n = 96) | |||
Primary outcome | Â | |||
Time weighted average SpO2/FiO2 ratio, mean (SD) | 380 (86) | 338 (93) | 42.1 (16.7–67.5) | 0.001 |
Secondary outcomes | ||||
Respiratory failure by PED7, No. (%) | 34 (35.4) | 50 (52.0) | 2.2 (1.2–3.8)†| 0.007‡ |
Pulmonary complication severity score | 2 (2, 2) | 2 (2, 3) | 2.3 (1.3–4.2)§ | 0.005‡ |
Use of HFNC or NIV, No. (%) | 7 (7.3) | 20 (20.8) | − 13.5 (− 23.2 to − 3.9) | 0.007* |
Use of new IMV, No. (%) | 1 (1.0) | 2 (2.0) | − 1.0 (− 4.5 to 2.5) | 0.56* |
No ventilatory support days by POD 7, median (IQR), d | 6.0 (5.8, 6.0) | 5.9 (5.0, 6.0) | NA | 0.03ll |