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Table (abstract P079) Primary and secondary outcomes

From: 44th International Symposium on Intensive Care & Emergency Medicine

Variables

Ventilation strategy

Odds ratio (95% CI)

or absolute difference (95% CI)

p value

Unadjusted

Sigh

(n = 96)

Conventional

(n = 96)

Primary outcome

 

Time weighted average SpO2/FiO2 ratio, mean (SD)

380 (86)

338 (93)

42.1 (16.7–67.5)

0.001

Secondary outcomes

Respiratory failure by PED7, No. (%)

34 (35.4)

50 (52.0)

2.2 (1.2–3.8)†

0.007‡

Pulmonary complication severity score

2 (2, 2)

2 (2, 3)

2.3 (1.3–4.2)§

0.005‡

Use of HFNC or NIV, No. (%)

7 (7.3)

20 (20.8)

− 13.5 (− 23.2 to − 3.9)

0.007*

Use of new IMV, No. (%)

1 (1.0)

2 (2.0)

− 1.0 (− 4.5 to 2.5)

0.56*

No ventilatory support days by POD 7, median (IQR), d

6.0 (5.8, 6.0)

5.9 (5.0, 6.0)

NA

0.03ll

  1. PED, postextubation day; IMV, invasive mechanical ventilation; POD, postoperative day; HFNC, high-flow nasal cannula; NIV, non-invasive mechanical ventilation.
  2. †Common odds ratio for a lower severe respiratory failure in the sigh vs conventional groups.
  3. ‡Ordinal logistic regression.
  4. §Common odds ratio for a lower pulmonary complication severity score in the sigh vs conventional groups.
  5. llMann-Whitney U test.