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Fig. 3 | Critical Care

Fig. 3

From: Cardiovascular effects of lactate in healthy adults

Fig. 3

Effect of each treatment on cardiac parameters. Measurements during infusion with half-molar sodium lactate (LAC) infusion and hypertonic sodium chloride (SAL). Time = 0 indicates baseline before infusion. A–C Preload parameters left ventricular end-diastolic volume (LVEDV), left atrial (LA) volume, and ratio of early (E) diastolic mitral inflow velocity and early diastolic mitral plane tissue velocity (e’) remained lower during LAC compared with SAL infusion. D–F Systolic blood pressure (sBP) remained lower during LAC compared with SAL infusion and systemic vascular resistance (SVR) and arterial elastance (Ea) were significantly reduced during LAC infusion. G–I Contractility measures preload recruitable stroke work (PRSW) and left ventricular stroke work normalized to end-diastolic volume (LVSW/EDV) were increased during LAC infusion, while end-systolic elastance (Ees) did not differ significantly. Data are shown as mean, with bars indicating SEM. † indicates P < 0.05 between treatments at a given time point

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Critical Care

ISSN: 1364-8535