Fig. 3
From: REmoval of cytokines during CArdiac surgery (RECCAS): a randomised controlled trial

Cytokine IL-2, IL-8, IL-10, TNF-alpha dynamic after HA. Boxplots depicting the levels of cytokine IL-2 (A), IL-8 (B), IL-10 (C) and TNF-alpha (D) before surgery (baseline) and during the course of intensive care unit (ICU) treatment (admission, day 1 (d1), and day 2 (d2) at ICU) comparing the control group (white bars, n = 19) to the treatment group (dark grey bars, n = 19) receiving haemoadsorption (HA) during cardiothoracic surgery with cardiopulmonary bypass (CPB). Variables are presented as boxplots (10th–90th percentile, median, plus mean values). Statistical analysis: Mann–Whitney-U-test of raw data after normality testing (Kolmogorov–Smirnov). *p < 0.05. N = 38