Fig. 1

Flow Diagram of Study Design. Consolidated Standards of Reporting Trials (CONSORT) flow diagram of the study design depicting recruiting and dropouts of the REmoval of Cytokines during CArdiac Surgery [2] trial. N = 38. Abbreviations C3a, complement component 3a; CPB, cardiopulmonary bypass; HA, haemoadsorption, AIDS, acquired immunodeficiency syndrome; ARF score, acute renal failure score; ASA, American Society of Anesthesiologists; CBP, cardiopulmonary bypass; CD4, cluster of differentiation 4, Cl, cardiac output; EF, ejection fraction, EuroSCORE, European System for Cardiac Operative Risk Evaluation; GEDI, Global End-Diastolic Volume Index, GFR, glomerular filtration rate; HA, haemoadsorption; ICU, intensive care unit; IL, interleukin, MAP, mean arterial pressure; NuDESC, Nursing Delirium Screening Scale; NYHA, New York Heart Association; PCT, procalcitonin; RRT, renal replacement therapy, SOFA, sequential organ failure assessment; TNF-a, tumor necrosis factor alpha; PaO₂/FiO₂, ratio of arterial oxygen partial pressure to fractional inspired oxygen