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Table 3 Length of ICU stay in pooled analysis (patients with an ICU stay, mITT population)

From: Length of hospital and intensive care unit stay in patients with invasive candidiasis and/or candidemia treated with rezafungin: a pooled analysis of two randomised controlled trials

 

Rezafungin

(N = 55)

Caspofungin

(N = 71)

Absolute difference

Relative difference

Unadjusted mean (SD)a, days

16.1 (15.2)

21.6 (18.0)

5.5

1.34 (95% CI 0.96,1.86)

ICU LoS Adjusted mean (95% CI)a LoS, days

17.3 (13.4,20.6)

21.4 (17.3,26.8)

4.1

1.24 (0.89,1.72)

  1. CI, confidence interval; ICU, intensive care unit; LoS, length of stay; mITT, modified intention to treat; SD, standard deviation
  2. aGeneralised linear model, unadjusted or adjusted for mechanical ventilation status; c(C-R)/(C/R), where C is caspofungin and R is rezafungin. The data were log-transformed because of skewing. The estimate is the ratio of geometric means, with values > 1 indicating more time in the ICU in the caspofungin arm