Table 2 Characteristics of ICU population (from pooled mITT population)
In ICU at randomisation | In ICU at any time | |||
|---|---|---|---|---|
Rezafungin | Caspofungin | Rezafungin | Caspofungin | |
N (%) in ICU | 46 (33.1) | 67 (43.2) | 55 (39.6) | 71 (45.8) |
Age, years Mean (SD) < 65, n (%) | 61.6 (11.55) 25 (54.3) | 61.5 (14.11) 37 (55.2) | 61.4 (11.70) 30 (54.5) | 62.2 (14.09) 38 (53.5) |
Female, n (%) | 11 (23.9) | 23 (34.3) | 12 (21.8) | 24 (33.8) |
Final diagnosis, n (%) | ||||
Candidemia only | 33 (71.7) | 50 (74.6) | 40 (72.7) | 51 (71.8) |
Invasive candidiasis | 13 (28.3) | 17 (25.4) | 15 (27.3) | 20 (28.2) |
Mechanically ventilated, n (%) | ||||
Yes | 16 (34.8) | 33 (49.3) | 16 (29.1) | 33 (46.5) |
No | 30 (65.2) | 34 (50.7) | 39 (70.9) | 38 (53.5) |
Baseline Modified APACHE II Score | ||||
Mean | 17.3* (7.47) | 16.0 (8.23) | 16.5* (7.53) | 15.9 (8.18) |
< 20 | 28* (63.6) | 47 (70.1) | 36* (67.9) | 50 (70.4) |
≥ 20 | 16* (36.4) | 20 (29.9) | 17* (32.1) | 21 (29.6) |