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Table 3 Association of early epinephrine bolus with outcomes

From: Early bolus epinephrine administration during pediatric cardiopulmonary resuscitation for bradycardia with poor perfusion: an ICU-resuscitation study

Outcome

Difference (95% CI)

Relative Risk (95% CI)

P-value

Survival to hospital discharge with favorable neurologic outcomea

 

0.99 (0.82, 1.18)

0.89

Sustained ROSC

 

0.98 (0.87, 1.12)

0.80

Survival to hospital discharge

 

0.97 (0.82, 1.14)

0.70

Survival to hospital discharge with PCPC of 1, 2, or no change from baseline

 

1.10 (0.89, 1.35)

0.39

Total FSS at hospital discharge

− 0.62 (− 1.82, 0.57)

 

0.31

PCPC at hospital discharge

− 0.02 (− 0.46, 0.41)

 

0.91

Change from baseline to hospital discharge in FSS of survivors

− 0.42 (− 1.32, 0.48)

 

0.36

New morbidity (survivors only)

 

0.78 (0.54, 1.12)

0.19

  1. Bold value indicates the primary outcome
  2. aFavorable neurologic outcome was defined as a PCPC of 1, 2, 3, or no change from baseline
  3. FSS, Functional Status Scale; PCPC, Pediatric Cerebral Performance Category