Overall (N = 452) | Epinephrine bolus ≤ 2 min | P-value | ||
---|---|---|---|---|
Yes (N = 322) | No (N = 130) | |||
Immediate cause(s) of event | ||||
Respiratory decompensation | 266 (59%) | 182 (57%) | 84 (65%) | 0.14 |
Hypotension as immediate cause of event | 253 (56%) | 194 (60%) | 59 (45%) | 0.01 |
Arrhythmia | 43 (10%) | 30 (9%) | 13 (10%) | 0.86 |
Cyanosis without respiratory decompensation | 21 (5%) | 11 (3%) | 10 (8%) | 0.08 |
Duration of CPR (min) | 9.0 [4.0,24.0] | 9.0 [4.0,23.0] | 7.5 [3.0,26.0] | 0.88 |
Category of Duration of CPR (min) | 0.74 | |||
< 6 | 175 (39%) | 123 (38%) | 52 (40%) | |
6–15 | 113 (25%) | 82 (26%) | 31 (24%) | |
16–35 | 77 (17%) | 58 (18%) | 19 (15%) | |
> 35 | 87 (19%) | 59 (18%) | 28 (22%) | |
CPR timea | 0.53 | |||
Weekday | 235 (52%) | 162 (50%) | 73 (56%) | |
Weeknight | 83 (18%) | 62 (19%) | 21 (16%) | |
Weekend | 134 (30%) | 97 (30%) | 36 (28%) | |
Pharmacologic interventions during event | ||||
Epinephrine | 406 (90%) | 322 (100%) | 84 (65%) | < 0.001 |
Minutes to first doseb | 1.0 [0.0.,2.0] | 1.0 [0.0,1.0] | 3.0 [3.0,6.0] | |
Number of dosesb | 3.0 [1.0,6.0] | 3.0 [1.0,6.0] | 3.0 [1.0,5.5] | 0.80 |
Average interval between dosesc | 4.1 [3.2,6.0] | 4.0 [3.2,5.8] | 4.6 [3.1,6.3] | 0.42 |
Atropine | 69 (15%) | 49 (15%) | 20 (15%) | 1.00 |
Calcium | 198 (44%) | 154 (48%) | 44 (34%) | 0.01 |
Sodium bicarbonate | 237 (52%) | 187 (58%) | 50 (39%) | < 0.001 |
Vasopressin | 20 (4%) | 13 (4%) | 7 (5%) | 0.61 |
Amiodarone | 12 (3%) | 7 (2%) | 5 (4%) | 0.34 |
Lidocaine | 11 (2%) | 7 (2%) | 4 (3%) | 0.52 |
Fluid bolus | 124 (27%) | 96 (30%) | 28 (22%) | 0.08 |