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Table 2 The profile of PaO2, FiO2, and SOFA over the first three days of ICU admission in the matched cohort

From: The association of arterial partial oxygen pressure with mortality in critically ill sepsis patients: a nationwide observational cohort study

 

Conservative PaO2 (n = 1211)

Liberal PaO2 (n = 1211)

p-value

ICU day 1, median [IQR]

   

 PaO2, mm Hg

84.4 [71.2–112.0]

107.2 [92.0–134.0]

< 0.001

 FiO2, %

40.0 [28.0–60.0]

44.0 [32.0–60.0]

< 0.001

 SOFA, total

10.0 [8.0–13.0]

10.0 [8.0–13.0]

0.702

  Respiration

2.0 [1.0–2.0]

2.0 [1.0–3.0]

0.717

  Coagulation

1.0 [0.0–2.0]

1.0 [0.0–2.0]

0.405

  Liver

0.0 [0.0–1.0]

0.0 [0.0–1.0]

0.304

  Cardiovascular

4.0 [3.0–4.0]

4.0 [3.0–4.0]

0.955

  Central nervous system

2.0 [1.0–3.0]

2.0 [1.0–3.0]

0.031

  Renal

1.0 [0.0–2.0]

1.0 [0.0–2.0]

0.574

ICU day 2, median [IQR]

   

 PaO2, mm Hg

80.0 [71.0–100.0]

110.0 [93.4–132.0]

< 0.001

 FiO2, %

40.0 [28.0–50.0]

40.0 [30.0–50.0]

0.947

 SOFA, total

11.0 [8.0–13.0]

10.0 [8.0–12.5]

< 0.001

  Respiration

2.0 [1.0–3.0]

2.0 [1.0–2.0]

< 0.001

  Coagulation

1.0 [0.0–2.0]

1.0 [0.0–2.0]

0.171

  Liver

0.0 [0.0–2.0]

0.0 [0.0–1.0]

0.708

  Cardiovascular

3.0 [3.0–4.0]

3.0 [2.0–4.0]

0.042

  Central nervous system

2.0 [1.0–3.0]

2.0 [1.0–3.0]

0.092

  Renal

1.0 [0.0–2.0]

1.0 [0.0–2.0]

0.610

ICU day 3, median [IQR]

   

 PaO2, mm Hg

78.0 [69.0–94.5]

106.0 [91.9–127.4]

< 0.001

 FiO2, %

36.0 [28.0–50.0]

35.0 [28.0–40.0]

0.001

 SOFA, total

9.0 [7.0–13.0]

9.0 [6.0–12.0]

< 0.001

  Respiration

2.0 [1.0–3.0]

1.0 [1.0–2.0]

< 0.001

  Coagulation

2.0 [0.0–3.0]

2.0 [0.0–3.0]

0.259

  Liver

0.0 [0.0–2.0]

0.0 [0.0–2.0]

0.287

  Cardiovascular

3.0 [0.0–4.0]

3.0 [0.0–4.0]

0.053

  Central nervous system

1.0 [1.0–3.0]

1.0 [1.0–3.0]

0.732

  Renal

0.0 [0.0–1.0]

0.0 [0.0–1.0]

0.662

  1. PaO2 Partial pressure of oxygen in arterial blood, FiO2 Fraction of inspired oxygen, SOFA Sequential organ failure assessment, ICU Intensive care unit, IQR Interquartile range.
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Critical Care

ISSN: 1364-8535