Table 1 Baseline characteristics of 28-day survivors and non-survivors
Survivors n = 58 | Non-survivors n = 25 | p | |
|---|---|---|---|
Age (years), mean (SD) | 60.3 (17.5) | 63.2 (17.8) | 0.50 |
Sex (male), n (%) | 38 (65.5) | 13 (52.0) | 0.24 |
APACHE IIa, mean (SD) | 18.2 (5.0) | 22.6 (5.8) | <0.001 |
SOFA scorea, mean (SD) | 6.9 (2.4) | 8.6 (3.2) | 0.009 |
ICU type, n (%) | 0.72 | ||
Medical | 30 (51.7) | 14 (56.0) | |
Surgical | 28 (48.3) | 11 (44.0) | |
Source of infection, n (%) | 0.94 | ||
Lung | 22 (37.9) | 9 (36.0) | |
Abdomen | 11 (19.0) | 5 (20.0) | |
Urinary tract | 8 (13.8) | 5 (20.0) | |
Bone or soft tissue | 7 (12.1) | 1 (4.0) | |
Central line | 3 (5.2) | 1 (4.0) | |
Endocarditis | 2 (3.5) | 1 (4.0) | |
Undetermined | 5 (8.6) | 3 (12.0) | |
Culture positive, n (%) | 35 (60.3) | 14 (56.0) | 0.71 |
Organism, n (%) | 0.88 | ||
Gram-negative | 14 (24.1) | 7 (28.0) | |
Gram-positive | 10 (17.2) | 3 (12.0) | |
Mixed | 7 (12.1) | 2 (8.0) | |
Fungal | 1 (1.7) | 1 (4.0) | |
Viral | 3 (5.2) | 1 (4.0) | |
Co-morbidities, n (%) | |||
Coronary artery disease | 15 (25.9) | 6 (24.0) | 0.55 |
Cerebrovascular disease | 9 (15.5) | 1 (4.0) | 0.13 |
Congestive heart failure | 16 (27.6) | 8 (32.0) | 0.79 |
Diabetes | 21 (36.2) | 3 (12.0) | 0.034 |
Chronic renal insufficiency | 14 (24.1) | 4 (16.0) | 0.56 |
Liver disease | 4 (6.9) | 3 (12.0) | 0.42 |
COPD | 14 (24.1) | 2 (8.0) | 0.13 |